Trimethoprim

[Micne ahaan] Proloprim; Trimpex; Bakteeriyo
[CAS MAYA. ] 738-70-5  
[Foomka Molecular] C14H18N4O3
[Miisaanka jirka] 290.323
[Muuqaalka] Budada Cad
[Nadaafad] 99% min
[Hawlaha Ugu Muhiimsan] 
1. Waxaa loo adeegsan karaa dawooyin ka hortag ah antimicrobial; sidoo kale waxaa loo isticmaali karaa daaweynta cudurada bakteeriyada iyo coccidiosis ee digaagga. 
2. Waa sheeko cusub oo afka laga maamulo oo ah antibiyootigyo baahsan. Waxay leedahay nooc bakteeriyada la mid ah oo leh daawooyinka sulfa laakiin leh awood ka xoog badan. Waxay wax ku ool u tahay daaweynta noocyo kala duwan oo Gram ah bakteeriya togan iyo mid taban. Maaddaama bakteeriyadu ay fududahay in loo beddelo iska caabbinta daroogada ee badeecadan, kuma haboona in keligiis loo isticmaalo daawada antimicrobial. Isku-darka u dhexeeya daawooyinka trimethoprim iyo sulfa waxay kor u qaadi karaan waxqabadka bakteeriyada dhowr jeer illaa dhowr iyo toban jeer. Badeecada waxaa badanaa loo isticmaalaa inay noqoto dawooyinka isku-dhafan ee dawooyinka sulfonamide oo leh saamiga guud ee 1: 5 ee isticmaalka. Waxaa sidoo kale loo isticmaali karaa sidii daawo xoolaha oo lagu daaweeyo sepsis avian oo ay sababto Escherichia coli, salmonellosis, digaaga dufanka, daacuunka, iyo habka neefsashada jeermiska labaad Waxaa sidoo kale loo isticmaali karaa daaweynta coccidiosis.  
[Codsi]
Waxaa loo adeegsaday dawooyinka iswada ee bakteeriyada; daaweeyaa infekshinka mareenka neef mareenka, infekshinka kaadi mareenka iyo infekshannada ku dhaca mindhicirka marka keli loo isticmaalo.
Ku saabsan Trimethoprim
Trimethoprim waa lipophilic daciif ah aasaasiga pyrimethamine bacteriostatic wakiil, budada cad ama cad-cad ee heerkulka qolka, ur aan lahayn, qadhaadh, wax yar ku milma chloroform, wax yar ku milma ethanol ama acetone, ku dhowaad aan ku milmin biyaha, fududahay in loo isticmaalo glacial acetic acid . Qeybta bakteeriyada waxay la mid tahay tan daawooyinka sulfa, laakiin waxay leedahay saameyn xoog leh oo bakteeriyada ah. Waxay waxtar u leedahay ka hortagga Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae, Staphylococcus aureus, iyo bakteeriyada kala duwan ee Gram-positive iyo negative, laakiin waxtar kuma leh cudurka Pseudomonas aeruginosa. Badanaa wax ka yar 10mg / L, hal adeegsi waa sahlan tahay in la keeno iska caabinta bakteeriyada, guud ahaan keligeed looma isticmaalo, badanaa daawooyinka sulfa waxay ka kooban yihiin isku diyaarin isku dhafan, caafimaad ahaan waxaa loo isticmaalaa in lagu daaweeyo infekshinka kaadi mareenka, infekshinka mindhicirka, infekshinka mareenka neef mareenka, kaadi-mareenka, enteritis , tiifowga, qoorgooyaha, otitis media, qoorgooyaha, sepsis iyo infekshannada unugyada jilicsan. Waxtarka qandhada tayfoodh iyo qandhada paratyphoid ma ahan mid ka hooseeya tan ampicillin, sidoo kale waxaa lagu dari karaa dawooyinka sulfa ee muddada dheer shaqeynaya si looga hortago loona daweeyo cudurka duumada ee falciparum ee daawada u adkeysata.