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  2. Forskolin

Forskolin

Forskolin

[CAS No.] 66428-89-5
[Foomka Molecular] C22H34O7
[Miisaanka Molecular] 410.51
[Solubility] Ku milmi kara dareeraha dabiiciga sida ethanol, chloroform iyo DMSO
[Isha dhirta] Coleus forskohlii （Willd.） Briq.
[Muuqaalka] budada jaalaha ah ee khafiifka ah
[Saamaynta Farmashiyaha] miisaanka oo yaraada, farshaxanka jirka.
Ku saabsan Forskolin
Forskolin waa nooc ka mid ah diterpene oo ka soo jeeda firfircoonida adenylate cyclase ee caleemaha caleemaha. Waa firfircooneeye biyo-kiciya oo kiciya waxqabadka adenylate cyclase ee unugyada naasleyda. Dhibaatooyinka anti-bararka iyo anti-oksidheer ee forskolin waxay sabab u tahay ka hortagga firfircoonaanta macrophage, taas oo hoos u dhigeysa heerarka thromboxane B2 iyo superoxide. Hantidan ayaa ka dhigaysa forskolin daawo wax ku ool ah oo loogu talagalay daaweynta cudurka wadnaha, dhiig karka, sonkorowga iyo neefta. Tijaabooyinka 'vitro' waxay muujiyeen in firfircoonida adenylate cyclase ee Forskolin ay keentay koror weyn oo heerarka AMP ee wareega ee unugyada kala duwan ee eukaryotic. Isku-darka hooseeya ee 'forskolin' wuxuu kordhin karaa wareegga dhiigga ee 'AMP cyclic AMP' qaddar yar iyadoo la xoojinayo firfircoonaanta adenylate cyclase ee unugyada aan wali taaban.

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