Mangiferin

[Magaca Magaca] Mangiferin, Mangifera Indica.Mangiferin
[Ku saabsan Mangiferin] 
Mangiferin, polyphenol dabiici ah ayaa loo yaqaanaa inuu soo bandhigo anti-bararka, antioxidant, iyo saameynta fayraska. Si kastaba ha noqotee habka molikuyuulka ee salka ku haya saameyntan si wanaagsan looma tilmaamin. Sababtoo ah NF-B ayaa door muhiim ah ka ciyaara howlahaan, waxaa suurtagal ah in mangiferin uu wax ka beddelo firfircoonaanta NF-B. Natiijooyinkayagu waxay muujinayaan in mangiferin uu xannibayo burooyinka necrosis factor (TNF) ee firfircoonaanta NF-B iyo hiddo-wadayaasha NF-B ee ku tiirsan sida ICAM1 iyo COX2. Saameynta waxaa lagu dhexdhexaadiyay iyada oo loo marayo ka hortagga firfircoonida IKK iyo xannibaadda fosforyaalka iyo hoos u dhigga IB .Intaa waxaa dheer, mangiferin wuxuu xakameynayaa TNF-ku-soo-kicinta fosforyaalka p65 iyo sidoo kale u-wareejinta nukleus wuxuuna sidoo kale xakameynayaa firfircoonaanta NF-B ee ay keeneen wakiillada kale ee caabuqa sida PMA , ceramide, iyo SA-LPS. Mangiferin, oo la mid ah antioxidants-ka kale ee loo yaqaan, NAC iyo PDTC, ayaa xakameynaya jiilka oxygen-ka ee dhexdhexaadka ah (ROI). Maaddaama heerarka intracellular glutathione (GSH) lagu yaqaan inay wax ka beddelaan heerarka NF-B, waxaan cabbirnay heerarka GSH. Mangiferin wuxuu kobciyaa heerka glutathione iyadoo kudhowaad 2-laab ka badan anti-oxidants kale, isla waqtigaasna wuxuu yareeyaa heerarka GSSG wuxuuna kordhiyaa waxqabadka catalase. Yaraynta GSH ee buthionine sulfoximine waxay horseeday dib ucelis weyn oo saameyn mangiferin ah. Sidaa awgeed mangiferin oo leh awooddeeda ah inay joojiso NF-B iyo kordhinta heerarka 'intracellular GSH' ayaa laga yaabaa inay caddeyso inay tahay daawo awood u leh daaweynta anti-bararka iyo daaweynta antioxidant. Mangiferin-dhexdhexaadinta hoos-u-dejinta NF-B sidoo kale waxay awood u leedahay daaweynta kiimikada-dhexdhexaadinta dhimashada unugyada, oo soo jeedinaysa doorka daaweynta isku dhafan ee kansarka. 
[Isha Dhirta]  Canscora decussata, caleen Mangifera indica L
[Qaaciddada Molecular iyo culeyska] C19H18O11,, 422.33
[Farshaxanka shaqada]   Anti-oksidation, anti-diabetes, anti lipid, antitumor ， Bakteeriyada iyo hagaajinta difaac, anti-virus
[Hanti jidheed] Budada kareem-yar-yar-yar, lagu milmi karo biyaha, methanol, ethanol, lipid
[Faahfaahinta]  Maadada firfircoon: Mangiferin, 60% -90% HPLC
[Muuqaalka]  Laga soo bilaabo Midab-huruud ilaa budada cagaaran ee huruudda ah
[Waxqabadka]
Mangiferin oo ka soo baxa caleemaha ayaa lagu soo warramey inuu leeyahay waxqabadyo antiinflammatory, dura, chloretic iyo cardiotonic wuxuuna muujiyaa firfircooni ka hortag badan oo bakteeriyada gram. Waxaa lagula taliyay inay daawo ahaan kahortagto astaamaha ilkaha. Mangiferin wuxuu muujinayaa saameyn antiviral ah oo ka dhan ah nooca I herpes simplex virus kaas oo waxtar u yeelan kara boomaatada anti-herpes (Unani Herbalist) 

  Hadaad rabto inaad waxbadan ka ogaato Mangiferin macluumaad, ku soo dhawow inaad nala soo xiriirto!