Hirudiin

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[CAS MAYA. ] 8001-27-2
[Formula Molecular] C287H440N80O113S7
[Miisaanka Molecular] Qiyaastii 7.0kDa, silsilad polypeptide aan glycosylated ahayn oo ka kooban 63 hadhaaga amino acid.
[Muuqaalka] Budada Cad
[Nadaafad]> 98.0%

[Waxqabadka]
1. Hirudin waa trombobin ka hortag ah oo leh hantida xinjirowga lidka ku ah dhiigga. 
2. Hirudin waxa uu leeyahay saamayn xoog leh oo ka hortagga thrombotic, hagaajinta boogaha, ka hortagga fibrosis, ka hortagga burooyinka iyo saamaynta hyperuricemia. 
3. Hirudin wuxuu kaloo saameeyaa dhibaatooyinka macaanka, dhiigbaxa maskaxda, iyo kuwa kale.

Ku saabsan Hirudiin
Hirudinka waa daawada xinjirowga lidka ku ah si dabiici ah u dhacda, ama dhiig khafiifiya, kaas oo ka yimid candhuufta caleenta daawada. Waxay ahayd mid ka mid ah dawooyinka xinjirowga lidka ku ah ee ugu horreeya ee la helay waxaana loo isticmaali jiray arrimo caafimaad qarniyo badan.
Hirudin wuxuu u shaqeeyaa isagoo xakameynaya thrombin, kaas oo ah enzyme ku lug leh habka xinjirowga. Marka la xannibo thrombin, hirudinka wuxuu ka hortagayaa samaynta xinjirowga dhiigga. Tani waxay faa'iido u yeelan kartaa xaaladaha caafimaadka qaarkood halkaasoo xinjirowga xad-dhaafka ah ay ku dhici karto, sida xinjirowga dhiigga ee qoto dheer, sambabada sambabada, ama xanuunada wadnaha qaarkood.
Waagii hore, hirudinka waxaa lagu heli jiray marka laga soo saaro qanjidhada calyada ee leeches. Si kastaba ha ahaatee, horumarka cilmiga bayoolajiga ayaa oggolaaday soo saarista hirudin synthetic ama recombinant, kaas oo hadda inta badan loo isticmaalo goobaha caafimaadka. Hirudinka synthetic ayaa faa'iido u leh in si ka sii diyaarsan loo helo oo lagu cabbiro awooddeeda.
Hirudin ayaa loo isticmaalay habab caafimaad oo kala duwan, oo ay ku jiraan ka hortagga xinjirowga dhiigga xilliga qalliinka, gaar ahaan xaaladaha heparin, oo ah daawada xinjirowga lidka ku ah ee kale ee caadi ahaan loo isticmaalo, ay ka hortagto. Waxa kale oo loo isticmaalay daawaynta xaaladaha wadnaha iyo xididdada dhiigga qaarkood, sida xanuunnada wadnaha ee degdega ah.