Oleanolic acid

[Magac kale] Oleanic acid
[CAS No.] 508-02-1
[Foomka Molecular] C30H48O3
[Miisaanka Molecular] 456.711
[Muuqaalka] Budada Cad
60% 70% 98%
[Waxqabadka] 
1. Yaraynta dhaawaca beerka: Oleanolic acid waa isku-darka triterpenoid pentacyclic, kaas oo leh saameyn difaac cad oo ku saabsan dhaawaca beerka ee ba'an iyo kuwa daba-dheeraada ee jiirka ee ay keento carbon tetrachloride.
2. Yaree dhaqdhaqaaqa plasma alanine aminotransferase: Oleanolic acid waxay leedahay saameyn muuqata oo ku saabsan dhimista enzyme ee xayawaanka leh cagaarshow ba'an iyo dabadheeraad ah iyo cirrhosis beerka.
3. Serum r-globulin ayaa hoos loo dhigay, waxayna la jaan qaadayaan hoos u dhigista jawaabaha caabuqa ee beerka la xiriira oo lagu arkay histology.
4. Kor u cusboonaysiinta hepatocytes: Oleanolic acid waxay si weyn u kordhin kartaa tirada wejiyada mitotic ee beerka haraaga ee jiirka, iyo heerka dib u soo kabashada ayaa ka sarreeya kan kooxda kantaroolka, taas oo soo jeedinaysa in ay leedahay saamaynta kor u qaadista dib u soo kabashada unugyada.
5. Yaraynta heerka tyrosine-ka ee isku-dhafka maskaxda ee jiirka cirrhosis beerka: Maadaama heerka tyrosine-ka ee homogenate maskaxda uu si weyn hoos ugu dhacay, waxay joojin kartaa jiilka-neurotransmitters, sidaas darteed waxay faa'iido u leedahay ka hortagga iyo daaweynta encephalopathy hepatic.
6. Xakamaynta fibrosis beerka: Jiirka beerka-cagaarshowga ee lagu daweeyay oleanolic acid, fibrosis beerka aad ayuu u daran yahay oo si weyn ayuu u yareeyay, waxa ku jira kolajka beerka ayaa yaraatay, taas oo soo jeedinaysa in ay leedahay saamaynta ka hortagga iyo daaweynta cirrhosis beerka.
7. Oleanolic acid waxay leedahay saameyn cad oo ka hortag ah oo ku saabsan nidaamka phagocyte mononuclear, macrophage phagocytic function iyo arthritis tijaabo ah, laakiin waxay saameyn ku leedahay shaqada difaaca humoral heterosexual iyo unugyada antigen-ku xidha. Kobcinta difaaca oo joojiso koritaanka khadka burada S180.
8. Waxay leedahay saameyn difaac ah oo ku saabsan dhaawaca koromosoomyada, waxay saameyn ka hortag ah ku leedahay atherosclerosis tijaabada ah, waxayna sidoo kale sixi kartaa cilladaha dheef-shiid kiimikaadka borotiinka.
Ku saabsan Oleanolic acid
Oleanolic acid waa nooc ka mid ah iskudarka triterpenoid pentacyclic kaas oo go'doonsan lagana soosaaray midhaha dhammaan geedaha geedaha gentian sagebrush ama midhaha Ligustrum lucidum. Waxay ku jirtaa qaab bilaash ah iyo glycoside ee poli Dhirta dhexdeeda, waxay noqotay daawada hepatoprotective caadi ahaan loo isticmaalo waxqabadka kiliinikada. Oleanolic acid waxay leedahay hawlaha anti-bararka, suuxinta, cardiotonic, diuretic, hypolipidemic, hypoglycemic, ilaalinta beerka iyo hoos u dhigista enzymes, kor u qaadida difaaca iyo xakameynta koritaanka S180 ee xanuunka burooyinka.
Oleanolic acid inta badan waxay leedahay hawlaha ilaalinta beerka iyo yaraynta enzymes, kor u cusboonaysiinta unugyada beerka, anti-bararka, xoojinta wadnaha, durayo, anti-buro, iwm. Waa qayb firfircoon oo ka mid ah horumarinta daawooyinka sida beerka. cudurka iyo hypoglycemia.